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DDU of Nasal Products

Recent developments in nasal delivery systems has resulted in greater focus on different uses for drug delivery. With great potential for rapid drug absorption into the turbinates and lymphoid tissues located at the back of the nasal cavity, focus has shifted to absorption into the systemic circulation and central nervous system for a wider range of treatments. There are three conventional technologies for nasal delivery: metered spray pumps (aqueous-based), nasal aerosols (propellant-based) and powder-based.

DDU of Nasal Sprays

Nasal Aerosols

Nasal Powders

DDU of Nasal Sprays

Nasal Aerosols

Nasal Powders

Nasal Aerosols

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DDU Over the Entire Contents

In the case of multiple dose devices, tests might need to be carried out throughout the life of the product i.e. dose uniformity over the entire contents.

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Semi-Automation Tools

Improve efficiency

Reduce variability

Eliminate handling errors

Increase testing capacity

Semi-Automation Tools

All of the tests involved in Delivered Dose Uniformity require the collection and drug recovery of individual doses into the collection tube of a Dosage Unit Sampling Apparatus (DUSA) appropriate to its type (MDI or DPI) prior to assay.