Automated Shake, Fire and Flow Control for MDIs, Nasal Sprays and Aerosols

Copley offers a range of ready-made flexible shake, fire and flow control systems for individual MDI testing with ACI, NGI, DUSA, waste shot collectors and other devices.

Vertus® Plus

Data collection records the key parameters during each test. Results can be stored locally, to a USB device or to a Local Area Network (LAN).

Touchscreen Display. Test methods are programmed using an intuitive touchscreen display. Once approved and saved, each method can be recalled.

Automatic Weighing. An integrated 4 or 5-place Mettler Toledo analytical balance is used to collect shot weight data at any point of the method.

The device is securely clipped into a holder, which in turn is clipped onto the Vertus. This allows most styles of device to be supported without the need to remove the canister from the device.

Shaking is performed using closed loop control, which assures that the required motion is achieved. It is precisely controlled, completely configurable and repeatable.

Firing can be configured to apply up to three distinct forces per actuation. These are typically used to set forces that detect, insert and fire the canister.

Safety standards are complied with: moving parts are enclosed and an emergency stop is easily accessible.

Optional: Temperature and Humidity Sensor provides accurate environmental condition information within the test area.

Interchangeable interface plates makes it easy to switch between collection device types

Optional: External printer

Vertus® Plus

Shot weight, the weight of the dose released during a single actuation, is routinely recorded as part of a DDU or APSD measurement. Useful for assessing the consistency of drug release from the inhaler, nasal drug product, routine measurement of shot weight is an efficient way to detect misfiring and more broadly, for analytical troubleshooting. Automation significantly streamlines the testing process when shot weight information is required.

Vertus® Plus is a fully automated benchtop shake and fire system, with integral shot weight measurement for MDI, nasal spray and nasal aerosol testing.

Offering all the functionality of Vertus® II, the Vertus Plus has an integrated weighing balance, which automatically records the mass of the inhaler at any point during a method. With Vertus Plus, even complete methods requiring shot weight collection can be fully automated, to the point of push button, walkaway operation, freeing analysts for more more productive tasks while at the same time improving data integrity.

Vertus Plus

Precision controlled, highly repeatable testing

The Vertus® series offers absolute control over a wide range of specific method parameters, including:

  • Shaking profile (including speed, angle and duration)
  • Time between shake and fire
  • Firing profile (including force, pause, fire down, rise and release time)
  • Air flow through system

Key Features: Vertus® Plus

Ph. Eur and USP compliant

21 CFR part 11 compliant

Offers precise control of test method parameters

Suitable for both DDU and APSD applications

The Vertus® Series – Automated Shake and Fire Systems for MDIs and Nasal Sprays

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Vertus® Plus Interface Plates

All Vertus® interface plates are interchangeable, meaning analysts can easily swap between collection devices. No tools are required, simply lift and switch!

Photos of some of the interface plates available are shown below. For a full list of available interface plates, contact us at

DUSA Stack with Waste Shot Collector Interface Plate

DUSA Interface Plate for Nasal Sprays

Next Generation Impactor NGI Interface Plate

Next Generation Impactor NGI with Glass Expansion Chamber

Andersen Cascade Impactor ACI Interface Plate

Andersen Cascade Impactor ACI with Alberta Idealised Nasal Inlet (AINI)

Static Eliminator

Are electrostatic charges causing issues for your MDI testing? Designed for use with the Vertus® II/Plus, our Static Eliminator has been shown to be effective in eliminating the unwanted variability that static introduces. Contact us to find out how the Static Eliminator can help with your testing.

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Vertus® Plus: Optional Extras

The optional features provide additional convenience and further functions to measure and record regulatory approved test methods as required by a particular application.

  • Internal airflow generation with automatic control and measurement
  • Automatic leak test to measure equipment integrity
  • Monitor and record of temperature and relative humidity
  • ER/ES compliance functionality
  • LIMS link so that results can results can be stored directly to a central information management system
  • DUSA Stack: a combined 4-DUSA & waste shot collector device for unattended high throughput operation with shot weights automatically recorded
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